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C9-ALS/FTD

There is 1 paper on C9-ALS/FTD in aging research: 1 observational study in people.

Disease

1 paper studies it1 more mentions it1 finding

See all 2 papers on C9-ALS/FTD

“blood-derived macrophages, whole blood and brain tissue from patients with C9-ALS/FTD all show an elevated type I interferon signature compared with samples from people with sporadic ALS/FTD”
C9orf72 in myeloid cells suppresses STING-induced inflammationNature2020doi:10.1038/s41586-020-2625-x
  • Humans1

Associations

1

Type I interferon signature

upin humans1

1 study

  1. C9-ALS/FTD is associated with type I interferon signature in humans (compared with sporadic ALS/FTD).

    “blood-derived macrophages, whole blood and brain tissue from patients with C9-ALS/FTD all show an elevated type I interferon signature compared with samples from people with sporadic ALS/FTD”

    Humanscompared with sporadic ALS/FTDblood-derived macrophages, whole blood and brain tissue

    C9orf72 in myeloid cells suppresses STING-induced inflammation

    Nature

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