Papers on STAT6

23 papers

Sunday, July 26

Chemico-biological InteractionsJul 26

DINCH exposure contributes to osteoarthritis pathogenesis via TSPO-mediated chondrotoxicity: Evidence from in silico prediction to experimental validation

Experiments in cellsBones and joints

Friday, July 17

Neuromolecular MedicineJul 17

STAT6 Targets the Autophagy Pathway to Regulate Microglial Senescence in Cognitive Impairment Caused by Cerebral Small-Vessel Disease

Experiments in ratsAutophagy

Thursday, June 11

Cell Death & DiseaseJun 11

Deficiency of G9a boosts muscle regeneration through IL13/Musclin-mediated crosstalk between macrophage and myofiber

Experiments in miceMuscle

Saturday, June 6

ADA Scientific Sessions 2026 AbstractJun 6

Macrophage OPA1 Prevents Age-Related Metabolic Dysfunction via the mtDNA-STING-STAT6 Pathway

Experiments in miceOPA1

Saturday, May 30

ImmunityMay 30

Immune signal restored B and T cell production in aged mice

Experiments in 18-month-old male mice tested interleukin 4; two four-week courses also improved immune, metabolic, physical and cognitive functions.Experiments in 18-month-old male mice tested interleukin 4; two four-week courses also improved immune, metabolic, physical and cognitive functions.

Mouse studyBlood and immune system

Tuesday, May 26

Clinical EpigeneticsMay 26

Epigenetic-Metabolic interplay in chronic kidney disease mortality: insights from grimage acceleration and transcriptomic profiling

Cohort study of 2,529 peopleGrimAge

Thursday, May 21

bioRxivMay 21

Older patients had more fused cells in three cancers’ metastases

An observational analysis examined cancer deposits from people with prostate, breast and lung cancers, finding an enrichment of these cells in elderly patients.An observational analysis examined cancer deposits from people with prostate, breast and lung cancers, finding an enrichment of these cells in elderly patients.

Preprint: cross-sectional studyMechanisms

Thursday, March 26

Biomedical ResearchMar 26

Spatiotemporal dynamics of exercise-induced macrophages influences axonal regeneration after peripheral nerve injury

Experiments in miceInterventions

Wednesday, February 25

Nature CommunicationsFeb 25

DNA-PK-mediated phosphorylation of STAT6 establishes a non-canonical type 2 immunity axis to prevent macrophage senescence

Experiments in miceCellular senescence

Tuesday, January 27

Acupuncture in MedicineJan 27

Electroacupuncture at ST25 combined with metformin improves intestinal function via the JAK/STAT pathway in a rat model of diabetes

Experiments in ratsMetformin

Friday, January 23

Cellular and Molecular Gastroenterology and HepatologyJan 23

Dietary Lauric Acid Suppresses Inflammation, Cholestasis, Hepatocyte Injury, and Senescence in 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine-induced Inflammatory Cholangiopathy

Experiments in miceInterventions

Tuesday, January 20

Nature CommunicationsJan 20

G9a-mediated H3K9me2 orchestrates intestinal epithelial regeneration through epigenetic silencing of cell cycle-related genes

Experiments in miceCell cycle regulation

Wednesday, January 24

ImmunityJan 24

Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging

Experiments in miceInterventions

Thursday, September 15

PLOS OneSep 15

Knockout of Trpa1 accelerates age-related cardiac fibrosis and dysfunction

Experiments in miceMechanisms

Tuesday, September 6

Pathology Oncology ResearchSep 6

Expression of SASP, DNA Damage Response, and Cell Proliferation Factors in Early Gastric Neoplastic Lesions: Correlations and Clinical Significance

Cohort study of 30 peopleDNA damage response

Monday, June 20

International Journal of Oral ScienceJun 20

Interleukin-13 promotes cellular senescence through inducing mitochondrial dysfunction in IgG4-related sialadenitis

Study in peopleCellular senescence

Thursday, April 1

Georgian Medical NewsApr 1

SIRT1 CONTRIBUTES TO POLARIZATION OF PERIPHERAL BLOOD MONOCYTES BY INCREASING STAT6 EXPRESSION IN YOUNG PEOPLE WITH OVERWEIGHT AND LOW-RISK OBESITY

Cross-sectional study of 30 peopleSirtuin signaling

Tuesday, December 1

AgingDec 1

Activation of adenosine A3 receptor reduces early brain injury by alleviating neuroinflammation after subarachnoid hemorrhage in elderly rats

Experiments in animalsInterventions

Wednesday, April 1

Bioscience ReportsApr 1

NAD+ attenuates experimental autoimmune encephalomyelitis through induction of CD11b+ gr-1+ myeloid-derived suppressor cells

Experiments in miceNAD+

Tuesday, June 6

The Journal of Clinical InvestigationJun 6

Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages

Experiments in miceMechanisms

Friday, October 21

Cell ReportsOct 21

IL4/STAT6 Signaling Activates Neural Stem Cell Proliferation and Neurogenesis upon Amyloid-β42 Aggregation in Adult Zebrafish Brain

Experiments in zebrafishJAK–STAT signaling

Thursday, August 25

Cell MetabolismAug 25

Caloric Restriction Leads to Browning of White Adipose Tissue through Type 2 Immune Signaling

Experiments in miceDietary restriction

Saturday, July 16

Doklady Biochemistry and BiophysicsJul 16

The role of STAT transcription factors in apoptosis regulation of hypothalamic neurons in aging in HER-2/neu transgenic mice and wild-type FVB/N mice

Experiments in miceApoptosis