What does the research say about STAT6?

STAT6

There is 1 paper on STAT6 in aging research: 1 observational study in people. The newest story, Oct 30, 2026: “Immune signal restored B and T cell production in aged mice”.

Biomarker

1 paper studies it22 more mention it

See all 23 papers on STAT6

Humans1

Latest

12 papers in 12 months

Pathology Oncology ResearchSep 6

Expression of SASP, DNA Damage Response, and Cell Proliferation Factors in Early Gastric Neoplastic Lesions: Correlations and Clinical Significance

Cohort study of 30 peopleDNA damage response

Paper

Chemico-biological InteractionsJul 26

DINCH exposure contributes to osteoarthritis pathogenesis via TSPO-mediated chondrotoxicity: Evidence from in silico prediction to experimental validation

Experiments in cellsBones and joints

Paper

Neuromolecular MedicineJul 17

STAT6 Targets the Autophagy Pathway to Regulate Microglial Senescence in Cognitive Impairment Caused by Cerebral Small-Vessel Disease

Experiments in ratsAutophagy

Paper

Cell Death & DiseaseJun 11

Deficiency of G9a boosts muscle regeneration through IL13/Musclin-mediated crosstalk between macrophage and myofiber

Experiments in miceMuscle

Paper

ADA Scientific Sessions 2026 AbstractJun 6

Macrophage OPA1 Prevents Age-Related Metabolic Dysfunction via the mtDNA-STING-STAT6 Pathway

Experiments in miceOPA1

Paper

ImmunityMay 30

Immune signal restored B and T cell production in aged mice

Experiments in 18-month-old male mice tested interleukin 4; two four-week courses also improved immune, metabolic, physical and cognitive functions.Experiments in 18-month-old male mice tested interleukin 4; two four-week courses also improved immune, metabolic, physical and cognitive functions.

Mouse studyBlood and immune system

Paper

Clinical EpigeneticsMay 26

Epigenetic-Metabolic interplay in chronic kidney disease mortality: insights from grimage acceleration and transcriptomic profiling

Cohort study of 2,529 peopleGrimAge

Paper

bioRxivMay 21

Older patients had more fused cells in three cancers’ metastases

An observational analysis examined cancer deposits from people with prostate, breast and lung cancers, finding an enrichment of these cells in elderly patients.An observational analysis examined cancer deposits from people with prostate, breast and lung cancers, finding an enrichment of these cells in elderly patients.

Preprint: cross-sectional studyMechanisms

Paper

Biomedical ResearchMar 26

Spatiotemporal dynamics of exercise-induced macrophages influences axonal regeneration after peripheral nerve injury

Experiments in miceInterventions

Paper

Nature CommunicationsFeb 25

DNA-PK-mediated phosphorylation of STAT6 establishes a non-canonical type 2 immunity axis to prevent macrophage senescence

Experiments in miceCellular senescence

Paper

See all 23 papers on STAT6