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Neurochemical Research

Sorafenib reduced cognitive deficits in desflurane-exposed mice

In 18-month-old mice of both sexes exposed to 2% desflurane for two hours, sorafenib pretreatment restored CLOCK protein and improved cognitive performance.In 18-month-old mice of both sexes exposed to 2% desflurane for two hours, sorafenib pretreatment restored CLOCK protein and improved cognitive performance.

Experiments in miceMechanisms
bioRxiv

Model infers spatial neighborhoods in dissociated single cells

The computational tool predicted cellular proximity across brain regions and identified age-associated neighborhood remodeling in an 8-month Alzheimer dataset.The computational tool predicted cellular proximity across brain regions and identified age-associated neighborhood remodeling in an 8-month Alzheimer dataset.

Preprint: computational studyAI & data