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Frontiers in Immunology

Microglial dectin-1/Clec7a in an alzheimer's disease model: a double-edged sword across the lifespan

By Xi Wen, Ramona M. Rodriguiz, William C. Wetsel, Mari L. Shinohara
Figure 1. Schematic of the Clec7aflox allele generation and the timeline of Clec7a deletion followed by mouse analysis.
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Figure 1. Schematic of the Clec7aflox allele generation and the timeline of Clec7a deletion followed by mouse analysis.Schematic of the Clec7aflox allele generation and the timeline of Clec7a deletion followed by mouse analysis.Xi et al.
Experiments in miceMechanisms

Declared no competing interests

Paper

The paper

Xi Wen, Ramona M. Rodriguiz, William C. Wetsel, Mari L. Shinohara

Duke University

Frontiers in Immunology, 3 Sep 2026

doi.org/10.3389/fimmu.2026.1864888PubMed 42755642

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