Senile plaques

3 papers

Animals1

Latest

4 in 12 months

Mathematical Medicine and Biology17 Jul

Predicting biological age using an accumulated neurotoxicity biomarker for amyloid beta oligomers

Computational studyBiomarkers

Zoo Biology4 May

Behavioral Characteristics of an Extremely Old Rhesus Macaque in a Zoo: Dementia-Like Symptoms and Implications for Quality of Life of Geriatric Animals

Experiments in monkeysMechanisms

PNAS6 Jan

Long-term effects of forty-hertz auditory stimulation as a treatment of Alzheimer's disease: Insights from an aged monkey model study

Experiments in 9 monkeysAlzheimer's disease

Brain and Nerve14 Nov

Brain Pathology of Cognitive Dysfunction in Aged Non-human Animals

ReviewMechanisms

Cell Biochemistry and Biophysics28 Apr

ABT263 Ameliorates Cellular Senescence, Aβ-Dependent Pathology and Cognitive Decline in Aged APP/PS1 Mice via Regulating PI3K/AKT/GSK-3β Pathways

Experiments in 16 miceInterventions

Aging Cell20 Jan

KIF9 Ameliorates Neuropathology and Cognitive Dysfunction by Promoting Macroautophagy in a Mouse Model of Alzheimer's Disease

Experiments in animalsInterventions

Brain Research7 Jan

Aging and voluntary exercise's effects on Aβ1-42 levels, endoplasmic reticulum stress factors, and apoptosis in the hippocampus of old male rats

Experiments in animalsInterventions

Aging30 Oct

Brain aging and Alzheimer's disease, a perspective from non-human primates

ReviewMechanisms

Atherosclerosis29 Sep

Lipids, lipoproteins, and apolipoproteins: Associations with cognition and dementia

ReviewPopulations

Cells27 Sep

Levels of Amyloid Beta (Aβ) Expression in the Caenorhabditis elegans Neurons Influence the Onset and Severity of Neuronally Mediated Phenotypes

Experiments in model organismsMechanisms