Chemokines

Biomarker

2 papers1 finding

Humans1

Upstream

Cellular senescence

upin cells1

1 study

Cellular senescence increases chemokines in cells.
“Senescent BECs induced by oxidative stress, DNA damage, or serum deprivation expressed a significantly higher level of chemokines to various degrees, when compared with control BECs.”
Cellsinduced by oxidative stress, DNA damage, or serum deprivation
Modulation of the microenvironment by senescent biliary epithelial cells may be involved in the pathogenesis of primary biliary cirrhosis
Journal of hepatology5 May 2010

Latest

54 in 12 months

Chinese Journal of GerontologyYesterday

Mechanism by which dental pulp cell SASP mediates chronic fibrosis in aged dental pulp through the CCL5-CCR5 axis

Experiments in human cellsSenescence-associated secretory phenotype (SASP)

Paper

bioRxiv9 Oct

Age-associated transcriptional programs in tumor-associated macrophages are associated with tumor progression in HPV-negative oral cancer

Preprint: computational studyInflammation

Paper

Journal of Cell Communication and Signaling8 Oct

Dermal fibroblasts cultured from aged human skin display a pro-inflammatory phenotype

Experiments in human cellsInflammation

Paper

Ageing Research Reviews8 Oct

Is there a role for senotherapeutics in the treatment of giant cell arteritis?

ReviewInterventions

Paper

Biochemistry Biokhimiia5 Oct

Astrocyte Structure-Function Relationship in Senescence and Neurodegeneration

ReviewCellular senescence

Paper

Translational Stroke Research2 Oct

Plasma CXCL10 links to higher stroke risk in older adults

Each 1-standard deviation higher CXCL10 was linked to 20% greater stroke risk over a median follow-up of 14 years.Each 1-standard deviation higher CXCL10 was linked to 20% greater stroke risk over a median follow-up of 14 years.

Cohort study of 1,175 peopleStroke

Paper

Age and Ageing1 Oct