Senescence biomarkers
5 papers2 findings
- Animals2
- Cells2
Interventions
2JM6
downin mice1
1 study
JM6
downin mice1
JM6 decreases senescence biomarkers in mice.
“relative to a decrease with JM6 KMO inhibition”
Animals5xFAD mice2 months
GSA 2025 abstract31 Dec 2025
3-hydroxykynurenine
upin mice1
1 study
3-hydroxykynurenine
upin mice1
3-hydroxykynurenine increases senescence biomarkers in mice.
“We saw an increase in senescence biomarkers with 3-HK (PAI-1, p21, IL-6, TIMP2) relative to a decrease with JM6 KMO inhibition.”
Animals5xFAD mice2 months
GSA 2025 abstract31 Dec 2025
Latest
22 in 12 monthsBritish Journal of Clinical Pharmacology
Therapeutic reversal of cellular senescence: A systematic review of senolytics, senomorphics and anti-ageing therapies in human clinical trials
Systematic review of studies in peopleSenolytics
The EMBO Journal
Cellular senescence: six decades of discovery and reinvention
ReviewCellular senescence
Research Square
Senescence Biomarkers Independently Predict Disease-Related Mortality in Chronic Kidney Disease
Preprint: cohort study in peopleChronic kidney disease
Journal of Visualized Experiments
Multiplexed Immunofluorescence Assay for Spatial Assessment of Senescence Markers in vivo
Study in peopleSenescence markers
Research Square
Biomarkers of Cellular Senescence and their Association with Frailty, Clinical Outcomes, and Survival in Multiple Myeloma
Preprint: cohort study of 59 peopleMultiple myeloma
The Journal of Infectious Diseases
Changes in Cellular Senescence Biomarkers Across Individuals at Different Stages of HIV Infection Before and After a Year on Antiretroviral Therapy
Cohort study in peopleCellular senescence
Placenta
Placenta tissue-based and circulating markers of cellular senescence in gestational diabetes mellitus
Case-control study of 40 peopleCellular senescence