ROS production

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1 paper1 finding

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Nanosecond pulsed electric field

downin human cells1

1 study
  1. Nanosecond pulsed electric field decreases ROS production in human cells.

    “These effects were confirmed by concurrent reductions in SA-β-Gal activity and in ROS production, and increases in EdU-positive (DNA-synthesizing) cells.”

    Cellsd-galactose-induced senescencehuman umbilical vein endothelial cells

    Nanosecond pulsed electric field applications rejuvenate aging endothelial cells by rescuing mitochondrial-to-nuclear retrograde communication

    Regenerative therapy18 Jun 2025

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Silencing LCN2 eases postoperative cognitive deficits in mice

AAV-mediated knockdown of LCN2 in aged mice limited microglial inflammation, reduced neuronal pyroptosis, and rescued memory following surgery.AAV-mediated knockdown of LCN2 in aged mice limited microglial inflammation, reduced neuronal pyroptosis, and rescued memory following surgery.

Preprint: experiments in miceMechanisms
The Journal of Biological Chemistry

Spiny mouse fibroblasts favor glycolysis and resist stress

Ear pinna fibroblasts from fetal, young, and old spiny mice maintained low-respiring, spherical mitochondria and stayed resistant to oxidative stress throughout the…Ear pinna fibroblasts from fetal, young, and old spiny mice maintained low-respiring, spherical mitochondria and stayed resistant to oxidative stress throughout the lifespan.

Experiments in cellsGlycolysis