ROS accumulation

Biomarker

1 paper1 finding

  • Model organisms1

Interventions

1

Quercitrin

downin worms1

1 study
  1. Quercitrin decreases ROS accumulation in worms.

    “inhibited ROS accumulation”

    Model organisms

    Antioxidant and anti-aging effects of quercetin 3-O-rhamnoside isolated from Houttuynia cordata Thunb extract on Caenorhabditis elegans

    Free radical biology & medicine14 Nov 2025

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Biogerontology

A metabolic protein promotes blood stem cell aging in mice

In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.

Experiments in miceMechanisms
Nano Research

Scaffold and metformin sped new bone formation in aged mice

A bone-supporting scaffold plus metformin accelerated new bone formation in aged mice, most clearly when bone-forming cells lacked a protein involved in energy…A bone-supporting scaffold plus metformin accelerated new bone formation in aged mice, most clearly when bone-forming cells lacked a protein involved in energy metabolism.

Experiments in miceMetformin
Nature Communications

Targeting a cell regulator reduced bone loss in mice

In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.

Experiments in miceBones and joints
Biochimica et Biophysica Acta General Subjects

Chelating intracellular calcium reduces fibroblast senescence and eases lung fibrosis

Treating cells and an in vivo fibrosis model with a calcium chelator delayed senescence markers, reduced collagen buildup, and dampened inflammatory secretions.Treating cells and an in vivo fibrosis model with a calcium chelator delayed senescence markers, reduced collagen buildup, and dampened inflammatory secretions.

Experiments in animalsCellular senescence