In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.In mice, genetically removing the protein reduced signs of cellular aging across multiple tissues and limited hallmarks of blood stem cell aging.
A bone-supporting scaffold plus metformin accelerated new bone formation in aged mice, most clearly when bone-forming cells lacked a protein involved in energy…A bone-supporting scaffold plus metformin accelerated new bone formation in aged mice, most clearly when bone-forming cells lacked a protein involved in energy metabolism.
In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.
Treating cells and an in vivo fibrosis model with a calcium chelator delayed senescence markers, reduced collagen buildup, and dampened inflammatory secretions.Treating cells and an in vivo fibrosis model with a calcium chelator delayed senescence markers, reduced collagen buildup, and dampened inflammatory secretions.