Respiratory chain complex activities

There are 10 papers on respiratory chain complex activities in aging research: 2 observational studies in people, 6 in animals, 1 in cells, 1 review.

Biomarker

10 papers study it5 more mention it3 findings

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  • Humans2
  • Animals6
  • Cells1

Associations

3

Frailty

downin humans1

1 study
  1. Frailty is associated with respiratory chain complex activities in humans (frailty categorized by the Fried Frailty Index).

    “respiratory chain complexes where only subjects categorized as frail by the Fried Frailty Index showed a significant decrease in activity.”

    Reviewfrailty categorized by the Fried Frailty Index

    A systematic review and meta-analysis of studies that have evaluated the role of mitochondrial function and iron metabolism in frailty

    Clinical and translational science

Alzheimer's disease-like pathology

downin rats1

1 study
  1. Alzheimer's disease-like pathology is associated with respiratory chain complex activities in rats (OXYS rats).

    “low activity of respiratory chain complexes I, IV, and V in cortical mitochondria”

    AnimalsOXYS ratscortical mitochondria

    The Rat Prefrontal-Cortex Transcriptome: Effects of Aging and Sporadic Alzheimer's Disease-Like Pathology

    The journals of gerontology. Series A, Biological sciences and medical sciences

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AD-like pathology

downin rats1

1 study
  1. AD-like pathology is associated with respiratory chain complex activities in rats.

    “including decreased activity of respiratory complexes against the background of greater fusion”

    Animalshippocampus

    Mitochondrial Dysfunction as a Predictor and Driver of Alzheimer's Disease-Like Pathology in OXYS Rats

    Journal of Alzheimer's disease : JAD

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Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 1May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 1Oct 2026: 0Nov 2026: 03 papers in 12 months

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