Nature Metabolism
Linked metabolic disruptions halt division in human cells
An engineered bacterial enzyme reversed the growth arrest by expanding a pool of molecules used to build cellular components in human connective-tissue cells grown in the…An engineered bacterial enzyme reversed the growth arrest by expanding a pool of molecules used to build cellular components in human connective-tissue cells grown in the lab.
Experiments in primary human fibroblastsInterventions
Limit: Senescence features are a proxy for cellular ageing, not a direct measure of it