Polyubiquitinated proteins

2 papers

Animals1
Model organisms1

Latest

2 in 12 months

bioRxiv3 Sep

Impaired proteostasis is an early feature of the diabetic heart in humans and mice

Preprint: experiments in miceInterventions

bioRxiv23 Feb

Validation of tissue-specific RNAi systems in C. elegans reveals a converging role for polyubiquitin UBQ-1/UBC in vitellogenin metabolism and lifespan

Preprint: experiments in wormsMechanisms

Learning & Memory6 Sep

Differential impacts of advanced age and sex in age-related trace fear memory impairment in rats

Experiments in ratsMechanisms

PLOS One14 Aug

The mitochondrial aspartate transporter Ucp4a regulates muscle aging and animal lifespan in Drosophila melanogaster

Experiments in fliesMitochondrion

Neuroscience17 Jun

Age-related dysregulation of proteasome-independent K63 polyubiquitination in the hippocampus and amygdala

Experiments in ratsUbiquitin–proteasome system

Autophagy8 Aug

Pharmacological inhibition of USP14 delays proteostasis-associated aging in a proteasome-dependent but foxo-independent manner

Experiments in model organismsInterventions

Brain Research Bulletin13 Jun

Dysregulation of baseline and learning-dependent protein degradation in the aged hippocampus

Experiments in ratsMechanisms

Aging Cell20 Mar

Aging-affiliated post-translational modifications of skeletal muscle myosin affect biochemical properties, myofibril structure, muscle function, and proteostasis

Experiments in fliesProteostasis

bioRxiv8 Nov

Ubiquitinated protein levels remain high during ageing in C. elegans

Preprint: experiments in model organismsMechanisms

Frontiers in Cell and Developmental Biology1 May

The proteasome: A key modulator of nervous system function, brain aging, and neurodegenerative disease

ReviewMechanisms