InterventionsAnimalsPreprint

Impaired proteostasis is an early feature of the diabetic heart in humans and mice

bioRxiv

Abstract

Diabetes and obesity increase cardiac lipid levels leading to cardiomyopathy and heart failure. We hypothesized that intermittent fasting would reduce cardiac lipid levels.

The paper

Rawnsley DR, Zhao C, Ma X et al.

bioRxiv · 3 Sep 2026 · CC BY · Preprint, not peer-reviewed

doi.org/10.64898/2026.09.01.748593