Papers on P16 mRNA

33 papers2 new in 30 days

Friday, October 16

PLOS OneOct 16

Identification of SGK1 as a candidate regulator associated with myeloid cell senescence in ME/CFS: An integrative transcriptomic and experimental study

Flowchart of the study design and analytical workflow.

Experiments in human cellsCellular senescence

Paper

Friday, May 8

PLOS OneMay 8

Ovarian gene activity linked to fertility decline in mice

Ovarian activity of p16, a gene involved in stopping cell division, rose 6.8-fold at 60 weeks compared with 4 weeks.Ovarian activity of p16, a gene involved in stopping cell division, rose 6.8-fold at 60 weeks compared with 4 weeks.

Mouse studyReproductive system

Paper

Thursday, January 1

American Journal of Translational ResearchJan 1

Protective effect of taurine on skin aging caused by deficiency of B cell-specific Moloney MLV insertion site-1

Experiments in miceTaurine

Paper

Sunday, June 1

Cellular and Molecular Gastroenterology and HepatologyJun 1

Differential MYC Phosphorylation Drives the Divergent Cholangiocyte Response to Stress

Study in peopleMYC

Paper

Wednesday, May 7

Scientific ReportsMay 7

ANXA2 regulates mitochondrial function and cellular senescence of PDLCs via AKT/eNOS signaling pathway under high glucose conditions

Experiments in human cellsNitric oxide–cGMP signaling

Paper

Friday, November 15

AgingNov 15

Adolescents and young adults with sickle cell disease exhibit accelerated aging with elevated T-cell p16INK4a expression

Cross-sectional study in peoplep16INK4a

Paper

Friday, September 13

Frontiers in AgingSep 13

Systematic transcriptomic analysis and temporal modelling of human fibroblast senescence

Computational studyAI & data

Paper

Friday, August 16

American Journal of Physiology Heart and Circulatory PhysiologyAug 16

FBXL19 in endothelial cells protects the heart from influenza A infection by enhancing antiviral immunity and reducing cellular senescence programs

Experiments in miceCellular senescence

Paper

Wednesday, July 3

Nature MedicineJul 3

Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial

Randomized trial in 60 peopleSenolytics

Paper

Friday, April 21

Experimental GerontologyApr 21

Correlations between biomarkers of senescent cell accumulation at the systemic, tissue and cellular levels in elderly patients

Cross-sectional study of 38 peopleBiomarkers

Paper

Thursday, July 14

Frontiers in AgingJul 14

Removal of p16 INK4 Expressing Cells in Late Life has Moderate Beneficial Effects on Skeletal Muscle Function in Male Mice

Experiments in miceMuscle

Paper

Tuesday, May 3

Clinical and Experimental Dental ResearchMay 3

Analysis of senescence in gingival tissues and gingival fibroblast cultures

Experiments in miceCellular senescence

Paper

Wednesday, February 16

CellsFeb 16

Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging

Experiments in miceCellular senescence

Paper

Wednesday, October 27

GeroScienceOct 27

Divergent regulation of lncRNA expression by ischemia in adult and aging mice

Experiments in miceMechanisms

Paper

Thursday, August 5

Scientific ReportsAug 5

Acute ischemic stroke triggers a cellular senescence-associated secretory phenotype

Experiments in miceSenescence-associated secretory phenotype (SASP)

Paper

Saturday, June 5

Radiation ResearchJun 5

Radiation-Induced Senescence in p16+/LUC Mouse Lung Compared to Bone Marrow Multilineage Hematopoietic Progenitor Cells

Experiments in miceCellular senescence

Paper

Tuesday, April 13

Biochemical and Biophysical Research CommunicationsApr 13

Dual disruption of eNOS and ApoE gene accelerates kidney fibrosis and senescence after injury

Experiments in miceCellular senescence

Paper

Friday, February 12

AgingFeb 12

SIRT6 enhances telomerase activity to protect against DNA damage and senescence in hypertrophic ligamentum flavum cells from lumbar spinal stenosis patients

Experiments in human cellsTransposable element activity

Paper

Wednesday, July 22

American Journal of Physiology Endocrinology and MetabolismJul 22

No effect of the endurance training status on senescence despite reduced inflammation in skeletal muscle of older individuals

Cross-sectional study of 34 peopleCellular senescence

Paper

Sunday, May 31

The Medical Journal of MalaysiaMay 31

Effect of kidney ischemia/reperfusion injury on proliferation, apoptosis, and cellular senescence in acute kidney injury in mice

Experiments in 6 miceApoptosis

Paper

Friday, January 17

Journal of Periodontal ResearchJan 17

Uncoupled inflammatory, proliferative, and cytoskeletal responses in senescent human gingival fibroblasts

Experiments in human cellsDNA damage response

Paper

Sunday, October 13

Aging CellOct 13

Downregulation of the inflammatory network in senescent fibroblasts and aging tissues of the long-lived and cancer-resistant subterranean wild rodent, Spalax

Experiments in animalsCellular senescence

Paper

Monday, April 29

Free Radical Biology & MedicineApr 29

Hsp22 overexpression induces myocardial hypertrophy, senescence and reduced life span through enhanced oxidative stress

Experiments in miceCellular senescence

Paper

Saturday, April 14

Journal of Medicinal FoodApr 14

Chia Seed Supplementation Reduces Senescence Markers in Epididymal Adipose Tissue of High-Fat Diet-Fed SAMP8 Mice

Experiments in miceInterventions

Paper

Thursday, January 11

Zhong Nan Da Xue Xue Bao Yi Xue BanJan 11

Role of high mobility group protein B1 in IL-1α-induced endothelial cell senescence

Experiments in human cellsCellular senescence

Paper

Tuesday, July 25

The Journal of PhysiologyJul 25

Decline in cellular function of aged mouse c-kit⁺ cardiac progenitor cells

Experiments in mouse cellsStem cell maintenance

Paper

Friday, November 25

The Journal of Frailty & AgingNov 25

Effect of Low-Dose Rapamycin on Senescence Markers and Physical Functioning in Older Adults with Coronary Artery Disease: Results of a Pilot Study

Non-randomized trial in 13 peopleRapamycin

Paper