PLOS One
Ovarian gene activity linked to fertility decline in mice
Ovarian activity of p16, a gene involved in stopping cell division, rose 6.8-fold at 60 weeks compared with 4 weeks.Ovarian activity of p16, a gene involved in stopping cell division, rose 6.8-fold at 60 weeks compared with 4 weeks.
Mouse studyReproductive system
Who was studiedFemale ICR mice
What changedOvarian p16 mRNA levels rose 6.8-fold at 60 weeks compared with 4 weeks
The catchOnly 10 mice per age group for molecular measurements