Each doubling of spermidine intake was associated with 2.6 millilitres per kilogram per minute higher peak oxygen uptake in older people with coronary artery disease.Each doubling of spermidine intake was associated with 2.6 millilitres per kilogram per minute higher peak oxygen uptake in older people with coronary artery disease.
In an external validation cohort, predicted peak VO₂ correlated with observed values at r = 0.654, with a root mean square error of 4.73 mL/kg/min.In an external validation cohort, predicted peak VO₂ correlated with observed values at r = 0.654, with a root mean square error of 4.73 mL/kg/min.