Oxidized lipids

Biomarker

2 papers

Cells2

Latest

9 in 12 months

bioRxiv2 Oct

Progressive behavioral and cognitive decline in Drosophila harboring AD- associated APOE4 variants

Preprint: experiments in fliesAPOE

Paper

bioRxiv29 Sep

Lack of dietary DHA drives harmful lipid remodeling and retinal degeneration in mice

Restoring the fatty acid reversed visual decline in mice and cleared toxic oxidized lipids that otherwise trigger chronic microglial activation.Restoring the fatty acid reversed visual decline in mice and cleared toxic oxidized lipids that otherwise trigger chronic microglial activation.

Preprint: experiments in miceEye

Paper

bioRxiv26 Sep

Lactate receptor activation reduces arterial senescence in mice

In progeroid mice, activating the GPR81 receptor with the agonist CHBA reduced arterial lipid buildup, lowered cellular senescence, and improved endothelial integrity.In progeroid mice, activating the GPR81 receptor with the agonist CHBA reduced arterial lipid buildup, lowered cellular senescence, and improved endothelial integrity.

Preprint: experiments in miceInterventions

Paper

Preprints.org11 Sep