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Oxidative capacity

There are 4 papers on oxidative capacity in aging research: 1 trial and 2 observational studies in people, 1 in animals. The newest story, Oct 27, 2026: “Muscle responds to home exercise in chronic kidney disease”.

Biomarker

4 papers study it276 more mention it4 findings

9 new papers in 30 daysSee all 280 papers on oxidative capacity

“CFPE and LC-PF indices were also positively associated with oxidative capacity (respectively r = 0.45, p = 0.06; r = 0.67, p = 0.004)”
Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adultsExperimental gerontology2019doi:10.1016/j.exger.2019.110723
  • Human trial1
  • Humans2
  • Animals1

Interventions

2

Biocompounds

upin mice1

1 study

  1. Biocompounds increase oxidative capacity in β-amyloid-induced mice.

    “Oxidative capacity was improved by exercise training and bioactive compounds.”

    Animalsin β-amyloid-induced mice8 weeks

    Effect of Linalool, Cineole, and β-Bourbonene Coupled with Aerobic Training on the Improvement of Presenilin-1/Amyloid Protein Precursor/Interleukin-1 beta/CASPASE 1 Network, Oxidative Capacity, and miRNA-210 in Mice with Alzheimer's Disease

    Archives of Razi Institute

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Aerobic exercise

upin mice1

1 study

  1. Aerobic exercise increases oxidative capacity in β-amyloid-induced mice.

    “Oxidative capacity was improved by exercise training and bioactive compounds.”

    Animalsin β-amyloid-induced mice8 weeks

    Effect of Linalool, Cineole, and β-Bourbonene Coupled with Aerobic Training on the Improvement of Presenilin-1/Amyloid Protein Precursor/Interleukin-1 beta/CASPASE 1 Network, Oxidative Capacity, and miRNA-210 in Mice with Alzheimer's Disease

    Archives of Razi Institute

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Upstream

1

Oxidative phosphorylation

no changein humans1

1 study

  1. Oxidative phosphorylation was not clearly linked with oxidative capacity in humans.

    “mitochondrial coupling was unrelated to oxidative capacity.”

    Humansvastus lateralis

    Neither intracellular oxygen availability nor mitochondrial coupling explain lower oxidative capacity in older human vastus lateralis muscle in vivo

    The Journal of physiology

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Associations

1

LC-PF index

upin humans1

1 study

  1. LC-PF index is associated with oxidative capacity in humans (basal, before RET) (r = 0.67, p = 0.004 (LC-PF index); r = 0.45, p = 0.06 (CFPE index)).

    “CFPE and LC-PF indices were also positively associated with oxidative capacity (respectively r = 0.45, p = 0.06; r = 0.67, p = 0.004)”

    Humansbasal, before RETskeletal muscle

    Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults

    Experimental gerontology

More on LC-PF index

Funding

1 grant since 2022

National Institute on Aging$471K

Latest

Dec 2025: 6Jan 2026: 7Feb 2026: 8Mar 2026: 6Apr 2026: 1May 2026: 2Jun 2026: 6Jul 2026: 5Aug 2026: 2Sep 2026: 4Oct 2026: 3Nov 2026: 454 papers in 12 months
American Journal of Physiology Renal Physiology

Muscle responds to home exercise in chronic kidney disease

A 12-week randomized trial in 25 people found that a personalized program increased muscles’ capacity to use oxygen.A 12-week randomized trial in 25 people found that a personalized program increased muscles’ capacity to use oxygen.

Randomized trial · 25 peopleResistance training
Paper
Journal of Nanobiotechnology

Microneedle patch improved muscle mass and endurance in mice

Researchers tested a patch designed to release muscle-targeted packages from human umbilical cord stem cells in mice with age-related muscle loss.Researchers tested a patch designed to release muscle-targeted packages from human umbilical cord stem cells in mice with age-related muscle loss.

Mouse studyMuscle
Paper
Nature Communications

Muscle enzyme buildup linked to type 2 diabetes in people

A randomized trial in people with type 2 diabetes found that exercise reduced buildup of the enzyme and improved the body’s response to insulin.A randomized trial in people with type 2 diabetes found that exercise reduced buildup of the enzyme and improved the body’s response to insulin.

Cross-sectional studyType 2 diabetes
Paper

See all 280 papers on oxidative capacity

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