Norepinephrine

Biomarker

2 papers2 findings

  • Human trial2

Interventions

1

Empagliflozin

downin humans1

1 study
  1. Empagliflozin decreases norepinephrine in humans.

    “Empagliflozin significantly reduced NE, with concomitant inverse changes in TIC.”

    Human trial6 months

    Sympathetic nervous system activity, tissue iron distribution, and their modulation by empagliflozin in the EMPATROPISM-FE trial

    Research Square3 Aug 2026Preprint

More on Empagliflozin

Associations

1

Tissue iron

upin humans1

1 study
  1. Norepinephrine is associated with tissue iron in humans (p<0.001).

    “In all tissues/organs, baseline TIC correlated closely with NE (all p<0.001).”

    Human trialbaseline

    Sympathetic nervous system activity, tissue iron distribution, and their modulation by empagliflozin in the EMPATROPISM-FE trial

    Research Square3 Aug 2026Preprint

More on Tissue iron

Funding

1 grant since 2022

National Institute on AgingUS$1.4m

Latest

Nov 2025: 0Dec 2025: 6Jan 2026: 1Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 6Sep 2026: 4Oct 2026: 321 in 12 months
bioRxiv

Restricting eating hours led to lasting fat loss in flies

In a fly experiment, ten days of restricted feeding reduced stored fat compared with unrestricted feeding, and the loss persisted when unrestricted feeding resumed.In a fly experiment, ten days of restricted feeding reduced stored fat compared with unrestricted feeding, and the loss persisted when unrestricted feeding resumed.

Preprint: experiments in fliesDietary restriction
bioRxiv

Normative brain models reveal dopamine shifts in early amyloid

In cognitively unimpaired older adults, intermediate amyloid burden showed lower dopamine-transporter deviation scores than amyloid-positive status, with an adjusted…In cognitively unimpaired older adults, intermediate amyloid burden showed lower dopamine-transporter deviation scores than amyloid-positive status, with an adjusted difference of −0.582.

Preprint: cohort study of 4,152 peopleBiomarkers