Muscle protein synthesis

2 papers1 finding

Human trial1

Interventions

1

High-intensity interval training

upin humans1

1 study

High-intensity interval training increases muscle protein synthesis in humans (1.3 ± 0.1 to 1.5 ± 0.1%·day−1).
“as did rates of MPS (1.3 ± 0.1 to 1.5 ± 0.1%·day−1 , P = 0.03).”
Human trialin comorbid octogenariansskeletal muscle4 weeksn = 28
The physiological impact of high-intensity interval training in octogenarians with comorbidities
Journal of cachexia, sarcopenia and muscle31 May 2021

More on High-intensity interval training

Funding

2 grants since 2019

Japan Society for the Promotion of ScienceJP¥21.7m

Latest

25 in 12 months

NutrientsYesterday

Protein and leucine added no measurable benefit in older men

In a 28-day randomised trial of 61 older men, extra protein or leucine added no measurable benefit overall during alternate-day fasting.In a 28-day randomised trial of 61 older men, extra protein or leucine added no measurable benefit overall during alternate-day fasting.

Randomised trial in 61 older men undergoing alternate-day fasting, 28 daysLeucine

Limit: Physical activity was not strictly controlled and could confound muscle outcomes

Cureus15 Oct

The Potential Therapeutic Effects of Testosterone on Sarcopenia: A Thorough Systematic Review

Systematic reviewTestosterone

Nutrients28 Sep

Leucine-Enriched Essential Amino Acids in Clinical Practice: A Narrative Review

Preprints.org16 Sep

Effects of Body-Mass-Scaled Protein and Leucine Supplementation on Body Composition and Cardiometabolic Blood Markers during Weight Loss in Older Men—A Randomized Controlled Trial

Preprint: randomised trial in 61 peopleLeucine

Frontiers in Nutrition11 Sep

Comparative effects of pea protein vs. dairy proteins (α-lactalbumin and casein) on aminoacidemia, exercise performance, gut microbiota, hormonal responses, neurocognitive function, mood, and metabolic-inflammatory responses in older adults

ReviewInterventions

The American Journal of Clinical Nutrition1 Sep

A self-selected vegan diet reduces skeletal muscle mass in healthy older adults: a randomized controlled trial

Randomised trial in 72 peopleMuscle

The Journal of Physiology24 Aug

Musculoskeletal and physiological responses to vortex wave stimulation in older adults

Non-randomised trial in 14 peopleInterventions

Preprints.org22 Aug

Dose Response of Leucine Intake on Muscle Preservation during Weight Loss in Young Adult Men—A Randomized Controlled Trial

Preprint: randomised trial in 80 peopleLeucine

Advances in Therapy22 Aug

Risk of protein intake deficiency during treatment with GLP-1 and GIP/GLP-1 receptor agonists: considerations for secondary sarcopenia

ReviewGLP-1 receptor agonists

The Journal of Nutrition17 Aug

Ingestion of 20 g of a Plant-derived Protein Blend With and Without Added Leucine or Whey Protein Does not Increase Muscle Protein Synthesis Rates in Older Males

Randomised trial in 45 peopleProtein