Papers on molecular markers

333 papers18 new in 30 days

Saturday, March 4

Mayo Clinic ProceedingsMar 4

Artificial Intelligence-Derived Electrocardiogram Assessment of Cardiac Age and Molecular Markers of Senescence in Heart Failure

Cohort study of 17 peopleHeart failure

Paper

Sunday, February 26

International Journal of Molecular SciencesFeb 26

Differentially Expressed Genes and Molecular Susceptibility to Human Age-Related Diseases

Experiments in ratsBiomarkers

Paper

Tuesday, February 21

PreprintFeb 21

Early life adversity is associated with phenotypic age but not delay discounting in chronologically young people

Preprint: cross-sectional study of 250 peoplePhenotypic Age

Paper

Sunday, February 12

Human GenomicsFeb 12

Data-driven identification and classification of nonlinear aging patterns reveals the landscape of associations between DNA methylation and aging

Computational studyDNA methylation

Paper

Sunday, February 5

Experimental GerontologyFeb 5

Longitudinal changes in blood pressure are preceded by changes in albuminuria and accelerated by increasing dietary sodium intake

Experiments in miceHypertension

Paper

Saturday, February 4

Alternative Therapies in Health and MedicineFeb 4

Calorie Restriction Combined with High-Intensity Interval Training Promotes Browning of White Adipose Tissue by Activating the PPARγ/PGC-1α/UCP1 Pathway

Randomized trial in 8 peopleDietary restriction

Paper

Sunday, January 1

Current Therapeutic Research, Clinical and ExperimentalJan 1

Evaluation of Rosuvastatin Therapy on SIRT1 Gene Expression in Patients with Multiple Sclerosis: An Uncontrolled Clinical Trial

Non-randomized trial in 25 peopleRosuvastatin

Paper

Saturday, December 31

European Journal of Applied PhysiologyDec 31

Effects of transdermal estrogen therapy on satellite cell number and molecular markers for muscle hypertrophy in response to resistance training in early postmenopausal women

Trial in peopleInterventions

Paper

Monday, December 12

International Journal of Molecular SciencesDec 12

Biological Age Predictors: The Status Quo and Future Trends

ReviewBiomarkers

Paper

Friday, December 9

BiomedicinesDec 9

Exploiting Signal Joint T Cell Receptor Excision Circle to Investigate the Impact of COVID-19 and Autoimmune Diseases on Age Prediction and Immunosenescence

Cross-sectional study in peopleAutoimmune disease

Paper

Wednesday, December 7

Ageing Research ReviewsDec 7

Loss of neuromuscular junction integrity and muscle atrophy in skeletal muscle disuse

ReviewMuscle

Paper

Wednesday, November 23

Life SciencesNov 23

Combined physical exercise reverses the reduced expression of Bmal1 in the liver of aged mice

Experiments in miceExercise

Paper

Monday, November 21

Aging CellNov 21

Cysteine restriction-specific effects of sulfur amino acid restriction on lipid metabolism

Experiments in miceDietary restriction

Paper

Thursday, November 3

Frontiers in AgingNov 3

Prohibitins in neurodegeneration and mitochondrial homeostasis

ReviewCellular homeostasis

Paper

Tuesday, November 1

Nature CommunicationsNov 1

Unsupervised learning of aging principles from longitudinal data

Experiments in miceBiomarkers

Paper

Tuesday, October 4

Molecular Therapy Methods & Clinical DevelopmentOct 4

SARS-CoV-2 infection increases the gene expression profile for Alzheimer's disease risk

Experiments in miceMechanisms

Paper

Sunday, October 2

Aging CellOct 2

Single-cell RNA-seq reveals early heterogeneity during aging in yeast

Experiments in yeastMechanisms

Paper

Thursday, September 22

Research SquareSep 22

Cell clustering in intervertebral disc degeneration: An attempted repair mechanism aborted via apoptosis?

Preprint: study of 55 peopleApoptosis

Paper

Monday, September 5

Sports Medicine - OpenSep 5

Physical Activity on Telomere Length as a Biomarker for Aging: A Systematic Review

Systematic review of studies in peoplePhysical activity

Paper

Wednesday, August 24

Aging CellAug 24

Metabolomic and transcriptomic signatures of influenza vaccine response in healthy young and older adults

Cohort study in peopleTryptophan–kynurenine metabolism

Paper

Wednesday, August 3

Molecular Medicine ReportsAug 3

LncRNA GAS5 promotes spermidine‑induced autophagy through the miRNA‑31‑5p/NAT8L axis in pulmonary artery endothelial cells of patients with CTEPH

Experiments in human cellsAutophagy

Paper

Sunday, July 3

BiogerontologyJul 3

Green tea EGCG effectively alleviates experimental colitis in middle-aged male mice by attenuating multiple aspects of oxi-inflammatory stress and cell cycle deregulation

Experiments in miceInterventions

Paper

Saturday, June 25

AntioxidantsJun 25

PPARδ Inhibits Hyperglycemia-Triggered Senescence of Retinal Pigment Epithelial Cells by Upregulating SIRT1

Experiments in human cellsSirtuin signaling

Paper

Friday, June 10

ContinuumJun 10

Neuropathology of Dementia Disorders

ReviewMechanisms

Paper

Tuesday, June 7

Behavioural Brain ResearchJun 7

Sevoflurane inhibits histone acetylation and contributes to cognitive dysfunction by enhancing the expression of ANP32A in aging mice

Experiments in miceEpigenetic regulation of gene expression

Paper

Thursday, May 26

Brain CommunicationsMay 26

Disentangling Alzheimer's disease neurodegeneration from typical brain ageing using machine learning

Study of 4,054 peopleAlzheimer's disease

Paper

Thursday, May 12

bioRxivMay 12

Accelerating the clock: Interconnected speedup of energetic and molecular dynamics during aging in cultured human cells

Preprint: experiments in human cellsMechanisms

Paper

Tuesday, April 26

Frontiers in MedicineApr 26

Prognostic Gene Expression Signature for Age-Related Hearing Loss

Experiments in ratsAge-related hearing loss

Paper

Saturday, April 23

DNA and Cell BiologyApr 23

Calorie Restriction-Regulated Molecular Pathways and Its Impact on Various Age Groups: An Overview

ReviewDietary restriction

Paper

Tuesday, March 22

Frontiers in GeneticsMar 22

Epigenetic Clock Deceleration and Maternal Reproductive Efforts: Associations With Increasing Gray Matter Volume of the Precuneus

Cross-sectional study of 51 peoplePopulations

Paper