2 papers3 findings
Nicotinamide mononucleotide
downin mouse cells1
Nicotinamide mononucleotide decreases mitochondrial oxidative stress in mouse cells.
“Imeglimin and NMN suppressed high glucose-increases in mitochondrial oxidative stress.”
Cellshigh glucose (25 mM)
ADA Scientific Sessions 2026 abstract5 Jun 2026
Imeglimin
downin mouse cells1
Imeglimin decreases mitochondrial oxidative stress in mouse cells.
“Imeglimin and NMN suppressed high glucose-increases in mitochondrial oxidative stress.”
Cellshigh glucose (25 mM)
ADA Scientific Sessions 2026 abstract5 Jun 2026
Methionine restriction
downin reviews1
Methionine restriction decreases mitochondrial oxidative stress.
“beneficial effects of MR could be explained in part by its ability to reduce mitochondrial oxidative stress”
Review
Methionine restriction beyond life-span extension
Annals of the New York Academy of Sciences24 Feb 2016
In ApoE-/- mice, rapamycin reduced aortic lipid-positive area from 25.32 ± 0.98% to 12.28 ± 1.49% and increased plaque efferocytosis index from 0.36 ± 0.02 to 1.37 ±…In ApoE-/- mice, rapamycin reduced aortic lipid-positive area from 25.32 ± 0.98% to 12.28 ± 1.49% and increased plaque efferocytosis index from 0.36 ± 0.02 to 1.37 ± 0.15.