IBA1-POSITIVE cells

2 papers

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Free Radical Biology & Medicine29 Aug

APOE4-AGE axis is linked to mtDNA release and cGAS-STING-mediated neuroinflammation in the aging brain

Experiments in micecGAS–STING signalling

Neurochemistry International26 Nov

Accelerated senescence exacerbates α-synucleinopathy in senescence-accelerated prone 8 mice via persistent neuroinflammation

Experiments in animalsMechanisms

Physiology & Behavior26 Aug

Aerobic exercise modulates RIPK1-mediated MAP3K5/JNK and NF-κB pathways to suppress microglia activation and neuroinflammation in the hippocampus of D-gal-induced accelerated aging mice

Experiments in animalsInterventions

Nature Neuroscience28 Mar

TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models

Experiments in miceOxidative phosphorylation

Nutrients18 Mar

Long-Term Caloric Restriction Attenuates β-Amyloid Neuropathology and Is Accompanied by Autophagy in APPswe/PS1delta9 Mice

Experiments in miceDietary restriction