Hydrogen peroxide
Biomarker2 papers2 findings
- Model organisms1
- Cells1
Interventions
1RSKS-1 mutation
upin worms1
1 study
RSKS-1 mutation
upin worms1
RSKS-1 mutation increases hydrogen peroxide in worms.
“observed an increase in hydrogen peroxide (H 2 O 2 ) levels in rsks-1(ok1255) mutants.”
Model organismsin rsks-1(ok1255) mutants
Peroxisomal enzyme ACOX-1.2 enables extended lifespan in long-lived roundworms · Current issues in molecular biology · 4 Sep 2026
Upstream
1Cellular senescence
upin human cells1
1 study
Cellular senescence
upin human cells1
Cellular senescence increases hydrogen peroxide in human cells.
“medium from senescent astrocytes failed to elicit this response and instead promoted hydrogen peroxide accumulation, ATP depletion and reduced cellular metabolic activity”
Cellsconditioned medium from senescent astrocytes applied to neuronsneuron
Senescent human astrocytes impair neuronal mitochondrial function through released factors · Antioxidants (Basel, Switzerland) · 6 Sep 2026
Latest
3Aqueous Extract of Buddleja globosa Modulates Oxidative Stress-Induced Senescence-Associated Responses in THP-1-Derived Macrophages
Peroxisomal enzyme ACOX-1.2 enables extended lifespan in long-lived roundworms
Inhibiting the fatty acid oxidation enzyme suppresses both autophagy and longevity in long-lived rsks-1 mutant Caenorhabditis elegans.
Current issues in molecular biology · Zhao Q et al.
Senescent human astrocytes impair neuronal mitochondrial function through released factors
Conditioned medium from damaged astrocytes alters extracellular mitochondria and triggers ATP depletion and oxidative stress in human postmitotic neurons.
Antioxidants (Basel, Switzerland) · Amorim P et al.