Frontiers in Cardiovascular Medicine·Nov 12IRF2BP2 3'UTR Polymorphism Increases Coronary Artery Calcification in MenStudy in peopleMechanismsPaper
Journal of Diabetes·Nov 3Relationships between type 2 diabetes, cell dysfunction, and redox signaling: A meta-analysis of single-cell gene expression of human pancreatic α- and β-cellsComputational studyAutophagyPaper
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi·Nov 1Urolithin A inhibits inflammation and oxidative stress induced by high lipid in hepatocytes via activating Nrf2 pathway and autophagyExperiments in human cellsUrolithin APaper
Molecular Biology of the Cell·Oct 28Analysis of senescence-responsive stress fiber proteome reveals reorganization of stress fibers mediated by elongation factor eEF2 in HFF-1 cellsExperiments in human cellsCellular senescencePaper
Ear and Hearing·Oct 27Extended High-frequency Hearing Impairment Despite a Normal Audiogram: Relation to Early Aging, Speech-in-noise Perception, Cochlear Function, and Routine Earphone UseCross-sectional study of 222 peopleEarPaper
Poultry Science·Oct 26Age-related changes in liver metabolism and antioxidant capacity of laying hensStudy of 192 chickensLipid and ceramide metabolismPaper
Annual Review of Pharmacology and Toxicology·Oct 13Brain-Protective Mechanisms of Transcription Factor NRF2: Toward a Common Strategy for Neurodegenerative DiseasesReviewNeurodegenerative diseasePaper
The Journal of Prevention of Alzheimer's Disease·Sep 30The Japan-Multimodal Intervention Trial for Prevention of Dementia (J-MINT): The Study Protocol for an 18-Month, Multicenter, Randomized, Controlled TrialStudy protocolMultidomain lifestyle interventionPaper
Alzheimer's & Dementia·Sep 30Preventing Alzheimer's disease within reach by 2025: Targeted-risk-AD-prevention (TRAP) strategyComputational studyInterventionsPaper
Antioxidants·Sep 29Lutein as a Modulator of Oxidative Stress-Mediated Inflammatory DiseasesReviewInterventionsPaper
Current Issues in Molecular Biology·Sep 26Resveratrol Ameliorates Aortic Calcification in Ovariectomized Rats via SIRT1 SignalingExperiments in ratsResveratrolPaper
Neuroscience Letters·Sep 26Tannic acid protects aged brain against cerebral hypoperfusion via modulation of Nrf2 and inflammatory pathwaysExperiments in ratsInterventionsPaper
BMC Musculoskeletal Disorders·Sep 21Ang-(1-7) protects skeletal muscle function in aged miceExperiments in miceMusclePaper
Blood Advances·Sep 21A simplified frailty score predicts survival and can aid treatment-intensity decisions in older patients with DLBCLCohort study of 784 peopleBiomarkersPaper
Journal for Immunotherapy of Cancer·Sep 18Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytesExperiments in miceMetforminPaper
Journal of Neuroinflammation·Sep 18MD2 contributes to the pathogenesis of perioperative neurocognitive disorder via the regulation of α5GABAA receptors in aged miceExperiments in miceMechanismsPaper
Saudi Journal of Biological Sciences·Sep 17Urolithin A prevents streptozotocin-induced diabetic cardiomyopathy in rats by activating SIRT1Experiments in ratsUrolithin APaper
Molecular Therapy Nucleic Acids·Sep 14ac4C acetylation of RUNX2 catalyzed by NAT10 spurs osteogenesis of BMSCs and prevents ovariectomy-induced bone lossExperiments in miceBones and jointsPaper
International Journal of Nanomedicine·Sep 14Novel Nanohydroxyapatite (nHAp)-Based Scaffold Doped with Iron Oxide Nanoparticles (IO), Functionalized with Small Non-Coding RNA (miR-21/124) Modulates Expression of Runt-Related Transcriptional Factor 2 and Osteopontin, Promoting Regeneration of Osteoporotic Bone in Bilateral Cranial Defects in a Senescence-Accelerated Mouse Model (SAM/P6). PART 2Experiments in miceOsteoporosisPaper
bioRxiv·Sep 11Exosomal MFGE8 from high glucose induced endothelial cells is involved in calcification/senescence of vascular smooth muscle cellsPreprint: experiments in human cellsCellular senescencePaper
Aging·Sep 9RNA N6-methyladenosine demethylase FTO promotes osteoporosis through demethylating Runx2 mRNA and inhibiting osteogenic differentiationExperiments in miceStem cell differentiationPaper
Experimental Gerontology·Aug 23The role of transient receptor potential ankyrin 1 in age-related endothelial dysfunctionExperiments in miceEndothelial dysfunctionPaper
Drug Design, Development and Therapy·Aug 20Quercetin Prevents Oxidative Stress-Induced Injury of Periodontal Ligament Cells and Alveolar Bone Loss in PeriodontitisExperiments in miceQuercetinPaper
Bone·Aug 18Age-associated changes in microRNAs affect the differentiation potential of human mesenchymal stem cells: Novel role of miR-29b-1-5p expressionStudy in peopleStem cell differentiationPaper
Pharmaceutical Biology·Aug 18Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathwayExperiments in animalsInterventionsPaper
Free Radical Biology & Medicine·Aug 9Ginsenoside Rg1 prevents bone marrow mesenchymal stem cell senescence via NRF2 and PI3K/Akt signalingExperiments in animalsInterventionsPaper
Journal of Clinical Medicine·Aug 8The Risk of Developing Osteoporosis in Hemolytic Anemia-What Aggravates the Bone Loss?Study in peoplePopulationsPaper
bioRxiv·Aug 5Specific telomere protection ensured by FOXO3a upon genotoxic stress and during agingPreprint: study in peopleTelomerase and telomere maintenancePaper