Expression of genes involved in energy metabolism, mitochondrial function, signaling, and oxidative stress response

1. Caloric restriction increases expression of genes involved in energy metabolism, mitochondrial function, signaling, and oxidative stress response in rhesus monkeys.

   “Genes that were overexpressed were mainly involved in pathways related to energy metabolism, mitochondrial function, signaling, and oxidative stress response.”

   Animalscompared with controlsskeletal muscle30% caloric restriction

   Caloric restriction reprograms skeletal muscle molecular pathways in non-human primates: potential relevance to human aging biology

   Skeletal muscle·8 May 2026

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