Skeletal muscle gene expression

Biomarker

2 papers2 findings

  • Humans2

Associations

2

HOMA-IR and physical activity

mixedin humans1

1 study
  1. HOMA-IR and physical activity is associated with skeletal muscle gene expression in humans.

    “HOMA-IR and physical activity appeared to have inverse and partially independent directions of association when adjusting for both traits in the same model.”

    HumansHOMA-IR and physical activity adjusted for each other in the same modelskeletal musclen = 263

    Activity and insulin resistance show opposite muscle gene links

    iScience24 Sep 2026

Performance fatigability

upin humans1

1 study
  1. Performance fatigability is associated with skeletal muscle gene expression in humans (1,935 differentially expressed genes).

    “A total of 1,935 differentially expressed genes were identified (DESeq2; adjusted for age, sex, and batch, false discovery rate adjusted p-value < 0.05).”

    Humansskeletal musclen = 724

    Performance Fatigability is Associated with Differential Gene Expression Patterns in Human Skeletal Muscle

    GSA 2025 abstract31 Dec 2025

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iScience

Activity and insulin resistance show opposite muscle gene links

In an observational study of 263 Finnish individuals, higher physical activity and lower insulin resistance were both linked to higher proportions of Type 1 nuclei.In an observational study of 263 Finnish individuals, higher physical activity and lower insulin resistance were both linked to higher proportions of Type 1 nuclei.

Cross-sectional study of 263 peopleInsulin resistance