ENDOTHELIN-1

2 papers

Human trial1

Funding

2 grants since 2025

National Heart, Lung, and Blood InstituteUS$857k

Endothelin-1 inhibits cardiomyocyte proliferation and heart regeneration
National Heart, Lung, and Blood InstituteWeill Medical Coll of Cornell UnivUS$818k2026–2030
Endothelin-1 signaling in microvascular responses to insulin and the role of physical activity and sedentary behavior in women with a history of gestational diabetes mellitus
National Heart, Lung, and Blood InstituteUniversity of IowaUS$38.9k2025–2028

Latest

5 in 12 months

Pregnancy Hypertension23 Sep

Prenatal aspirin use is associated with preserved vascular endothelial function measured after pregnancy in women with a history of preeclampsia

Cohort study in peopleAspirin

Lung16 Sep

GLP-1 Receptor Agonists in Pulmonary Hypertension: Mechanistic Rationale, Preclinical Evidence, and Clinical Knowledge Gaps

ReviewGLP-1 receptor agonists

Frontiers in Endocrinology6 Aug

Acute effects of "exercise snacks" on postprandial glucose and insulin responses in populations at metabolic risk: a meta-analysis with exploratory meta-regression and vascular outcomes

Meta-analysis of randomised trialsExercise

Frontiers in Cardiovascular Medicine4 Aug

Effects of HIIT and MICT on cardiovascular function in essential hypertension: roles of inflammation, oxidative stress, and RAS axis

Randomised trial in 56 peopleHigh-intensity interval training

AHA Scientific Sessions 2025 Abstract3 Nov

Estrogen receptor alpha inhibits right ventricle cardiomyocyte NLRP3 inflammasome activation and restores right ventricular contractile function in low estrogen states

Experiments in animalsInterventions