Emerin

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1

Perturbed cyclic strain

downin mouse cells1

1 study
  1. Perturbed cyclic strain decreases emerin in mouse cells.

    “mechanical induction of premature senescence was associated with decreases in the nuclear envelope protein emerin”

    Cellsmechanical induction of premature senescence

    Perturbed cyclic strain results in a mechanically-induced, premature senescent phenotype in cardiac fibroblasts

    bioRxiv (Cold Spring Harbor Laboratory)17 Mar 2025Preprint

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bioRxiv

Nuclear anchors weaken in senescent cultured human retinal cells

In a laboratory experiment, chemically induced senescent human retinal cells showed increased mobility and altered binding of proteins that anchor DNA to the nuclear…In a laboratory experiment, chemically induced senescent human retinal cells showed increased mobility and altered binding of proteins that anchor DNA to the nuclear scaffold.

Preprint: experiments in human cellsCellular senescence