ECM remodeling-associated gene expression

1. Ataxia telangiectasia is associated with ECM remodeling-associated gene expression in human cells.

   “Senescing A-T fibroblasts also exhibited a marked, intriguely complex alteration in the expression of genes associated with extracellular matrix (ECM) remodeling.”

   Cellssenescing ataxia-telangiectasia fibroblastsskin fibroblast3% oxygen

   Accelerated replicative senescence of ataxia-telangiectasia skin fibroblasts is retained at physiologic oxygen levels, with unique and common transcriptional patterns

   Aging cell·30 May 2023

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