Interferon-stimulated gene expression

Biomarker

2 papers1 finding

Humans1
Animals1

Associations

Cellular senescence

upin humans1

1 study

Cellular senescence is associated with interferon-stimulated gene expression in humans.
“Interferon-stimulated genes are elevated in senescent human beta cells, but genes encoding senescence-associated secretory phenotype (SASP) cytokines are not.”
Humanspancreatic beta cell
Senescence of human pancreatic beta cells enhances functional maturation through chromatin reorganization and promotes interferon responsiveness
Nucleic acids research29 Apr 2024

Latest

1 in 12 months

bioRxiv8 Oct

Older mice had delayed immune responses and recovery from flu

An experiment spanning 16 combinations of age, sex and infection stage also found persistent inflammatory responses in older male mice at later stages.An experiment spanning 16 combinations of age, sex and infection stage also found persistent inflammatory responses in older male mice at later stages.

Preprint: experiments in miceImmune response

Paper

bioRxiv6 Aug