Contractility

Papers on contractility

1,167 papers54 new in 30 days

Thursday, October 1

Wednesday, September 30

Saturday, September 26

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Wednesday, September 23

Tuesday, September 22

Sunday, September 20

Experimental Gerontology

Compound improved muscle function in aged male mice

In a four-week experiment, two-year-old male mice given P7C3 maintained grip strength, while it declined in mice given a control solution.In a four-week experiment, two-year-old male mice given P7C3 maintained grip strength, while it declined in mice given a control solution.

Figure from Experimental Gerontology
Mouse studyMuscle

Saturday, September 19

Thursday, September 17

Wednesday, September 16

Tuesday, September 15

Friday, September 11

Thursday, September 10

Aging Cell

Sustained enzyme activity weakened skeletal muscle in mice

In experiments, keeping a signaling enzyme active in young mice reduced muscle force after six weeks, before substantial muscle loss developed.In experiments, keeping a signaling enzyme active in young mice reduced muscle force after six weeks, before substantial muscle loss developed.

Aging is associated with reduced normalized TA mass and increased CaMKII abundance, and CaMKIICA overexpression increases CaMKII activity in young skeletal muscle.
Mouse studyMuscle

Wednesday, September 9

Friday, September 4

Tuesday, September 1

Sunday, August 30

Cell Reports

Supplement eased heart stress but disrupted bone marrow in mice

In mice that age early from mitochondrial DNA mutations, nicotinamide riboside steadied metabolism in the heart, whose cells no longer divide, but upset it in…In mice that age early from mitochondrial DNA mutations, nicotinamide riboside steadied metabolism in the heart, whose cells no longer divide, but upset it in fast-dividing bone marrow and worsened anemia.

Figure from Cell Reports
Mouse studyInterventions

Thursday, August 27

Wednesday, August 26

Nature Cell Biology

Excess cell contraction impairs implantation in mouse embryos

Experiments compared embryos from female mice aged 6–9 weeks and 40 weeks and found that excessive cell contraction hindered spreading during implantation.Experiments compared embryos from female mice aged 6–9 weeks and 40 weeks and found that excessive cell contraction hindered spreading during implantation.

Figure from Nature Cell Biology
Mouse studyMechanisms

Friday, August 21

Thursday, August 20

Tuesday, August 18

Sunday, August 16