MechanismsAnimals

Cardiomyocyte-intrinsic somatic mtDNA mutations induce an OXPHOS-dependent immune response and promote progressive heart failure

Science Advances

The paper

Bubb K, Rigoni G, Papadea P et al.

Science Advances · 4 Sep 2026

doi.org/10.1126/sciadv.aec8606 PubMed 42696572

Gut microbes fuel aging tied to mitochondrial defects in mice
bioRxiv · 5 Oct 2026
Mitochondrial TFAM limits CD8+ T cell lung damage in mice
bioRxiv · 2 Oct 2026
Persistent IFN-γ links to worse cardiac remodeling in aged mice
Journal of Molecular and Cellular Cardiology · 2 Oct 2026
Protein deficiency impaired memory in aging mice
NPJ Aging · 7 Oct 2026