bioRxiv
Excess cell size drives senescence by altering RNA in cells
Experiments in cultured cells show that cell enlargement reorganizes DNA and alters RNA splicing, while restoring a single protein variant resumes cell division.Experiments in cultured cells show that cell enlargement reorganizes DNA and alters RNA splicing, while restoring a single protein variant resumes cell division.
Preprint: human cell studyCellular senescence
Who was studiedCultured cells
What changedExcess cell size drove cellular senescence by altering RNA splicing in cultured cells
The catchCell size and senescence interactions were not measured in living animals