CD8+ T cell function

1 paper

Animals1

Latest

5 in 12 months

bioRxiv5 Oct

Nicotinamide riboside improves parasite control in mice

In mice infected with Trypanosoma cruzi, treatment with the NAD+ precursor improved CD8+ T-cell function and reduced parasite burden in blood and skeletal muscle.In mice infected with Trypanosoma cruzi, treatment with the NAD+ precursor improved CD8+ T-cell function and reduced parasite burden in blood and skeletal muscle.

Preprint: experiments in miceNicotinamide riboside

bioRxiv28 Sep

Mitochondrial TFAM limits CD8+ T cell lung damage in mice

In mice infected with influenza, CD8+ T cells lacking one TFAM copy provoked lung immunopathology without improving viral control and later lost recall immunity.In mice infected with influenza, CD8+ T cells lacking one TFAM copy provoked lung immunopathology without improving viral control and later lost recall immunity.

Preprint: experiments in miceTFAM

Science China Life Sciences15 Jan

CD8⁺ T cell aging, senescence, and related disease

ReviewCellular senescence

Nature Metabolism10 Dec

Dietary restriction reprograms CD8⁺ T cell fate to enhance anti-tumour immunity and immunotherapy responses

Experiments in miceDietary restriction

European Journal of Immunology14 Nov

Divergent Effects of Cytomegalovirus and Rheumatoid Arthritis on Senescent CD4⁺ T Cells

Cohort study in peopleCellular senescence

Science Advances26 Sep

Age-related remodeling of the sialoglycans dampens murine CD8⁺ T cell function

Experiments in animalsMechanisms

Science Translational Medicine10 Sep

Interferon-induced senescent CD8⁺ T cells reduce anti-PD1 immunotherapy efficacy in early triple-negative breast cancer

Cohort study of 171 peopleBlood and immune system

Virologica Sinica6 Jun

The slow progression of Japanese encephalitis in aged mice is likely associated to B cell recruitment in the brain

Experiments in miceBlood and immune system

Cell Communication and Signaling28 Apr

LAMA4⁺ CD90⁺ eCAFs provide immunosuppressive microenvironment for liver cancer through induction of CD8⁺ T cell senescence

Experiments in animalsMechanisms