AKT and mTOR phosphorylation

1. 20-hydroxyecdysone decreases AKT and mTOR phosphorylation in human cells.

   “Consistently, western blot analysis showed that β-Ecd suppressed Ang II-induced phosphorylation of AKT and mTOR.”

   Cellsangiotensin II treatmenthuman aortic smooth muscle cells

   β-Ecdysterone Attenuates Ang II-Induced Senescence in Human Aortic Smooth Muscle Cells via Autophagy Activation and ROS Suppression Through AKT/mTOR Pathway Inhibition

   Frontiers in bioscience (Landmark edition)·9 May 2026

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