Active caspase-1

3 papers study it8 more mention it

Human trial1
Animals1
Cells1

Latest

3 papers in 12 months

iScienceOct 18

Caloric restriction attenuates NLRP3 inflammasome activation and oxidative stress in leukocytes of patients with obesity

Non-randomized trial in 45 peopleDietary restriction

Cardiovascular DiabetologyFeb 13

Timing-dependent anti-inflammatory effects of empagliflozin in monocyte-derived macrophages from post-myocardial infarct patients with type 2 diabetes

Randomized trial in 66 peopleEmpagliflozin

International ImmunopharmacologyNov 20

AGK2 and nicotinamide riboside reveal SIRT2's protective role in a diabetic-dietary rat model of NASH via deacetylation of NLRP3, LKB1, and FOXO3a and restoration of AMPK-ACC/PGC-1α-Nrf2 signaling

Experiments in ratsNicotinamide riboside

NutrientsSep 25

Eicosapentaenoic Acid and Urolithin a Synergistically Mitigate Heat Stroke-Induced NLRP3 Inflammasome Activation in Microglial Cells

Experiments in mouse cellsUrolithin A

CellsJul 11

NLRP3 Inflammasome and Inflammatory Response in Aging Disorders: The Entanglement of Redox Modulation in Different Outcomes

ReviewNLRP3 inflammasome

The Journal of Clinical InvestigationFeb 4

RNase L represses hair follicle regeneration through altered innate immune signaling

Experiments in miceImmune response

Archives of Physiology and BiochemistrySep 26

Chronic whole-body heat treatment in obese insulin-resistant C57BL/6J mice

Experiments in miceInsulin resistance

Nature CommunicationsNov 19

Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to PPARA agonism and fasting

Experiments in animalsMechanisms

Nature CommunicationsSep 21

Telomere dysfunction activates YAP1 to drive tissue inflammation

Experiments in animalsMechanisms

MetabolismNov 8

HFD refeeding in mice after fasting impairs learning by activating caspase-1 in the brain

Experiments in animalsInterventions