10-year ASCVD risk

Biomarker1 paper2 findings

  • Humans1

Interventions

1

Tirzepatide

no changein humans1downin humans1−9.6% to −3.7%

1 study
  1. Tirzepatide has no effect on 10-year ASCVD risk in humans (-3.7%).

    Humanssubcutaneous12 monthsn = 275

    Cardiometabolic and atherosclerotic cardiovascular disease outcomes associated with tirzepatide: insights from a 1-year multicenter observational study · Journal of the Endocrine Society · 9 Sep 2026

  2. Tirzepatide decreases 10-year ASCVD risk in humans (-9.6%).

    Humansin individuals achieving at least 10% TBWLsubcutaneous12 months

    Cardiometabolic and atherosclerotic cardiovascular disease outcomes associated with tirzepatide: insights from a 1-year multicenter observational study · Journal of the Endocrine Society · 9 Sep 2026

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