Review1 Oct 2026

Melatonin and Diabetic Nephropathy: From Mechanistic Pathways to Translational Opportunities in Clinical Management

Current Medicinal Chemistry

The paper

Chapani MS, Ostadmohammadi K, Moulaei-Arani M et al.

Current Medicinal Chemistry · 25 Sep 2026

doi.org/10.2174/0109298673480116260915111102 PubMed

AnimalsmTOR & rapamycin1 h

Rapamycin reduces ferroptotic stress and shrinks atherosclerotic plaques in mice

The mTOR inhibitor restored macrophage efferocytosis and mitochondrial function while lowering aortic lipid burden in high-fat-fed ApoE-deficient mice.

International Immunopharmacology · Wang Y et al.

AnimalsCellular senescence1 h

Jianwei Shoutai Pills reduce uterine aging and pregnancy loss in aged mice

The herbal formula delayed thymic involution, restored regulatory T cell function, and improved maternal-fetal immune tolerance by altering metabolic signaling in aging female mice.

Phytomedicine · Guan F et al.

Cells1 h

Loss of lncRNA H19 suppresses osteoblast differentiation under oxidative stress

Overexpressing the noncoding RNA restored bone healing in mice, separating impaired osteogenesis from the onset of cellular senescence.

Bone · Shin HR et al.

CellsPreprint3 h

Aged human muscle secretes an enzyme that impairs stem cell maintenance

Profiling conditioned media revealed that altered sphingolipid signaling reduces muscle stem cell pools in human cell cultures.

bioRxiv · Crisol B et al.

Melatonin and Diabetic Nephropathy: From Mechanistic Pathways to Translational Opportunities in Clinical Management

The paper

Latest stories

Rapamycin reduces ferroptotic stress and shrinks atherosclerotic plaques in mice

Jianwei Shoutai Pills reduce uterine aging and pregnancy loss in aged mice

Loss of lncRNA H19 suppresses osteoblast differentiation under oxidative stress

Aged human muscle secretes an enzyme that impairs stem cell maintenance