Brain agingHuman trial

Hearing aids did not cut dementia conversion in older adults

Over 24 months, dementia conversion was 3.09% with hearing aids compared with 4.74% with hearing care education, a non-significant difference.

JAMA Neurology

In a randomized clinical trial of 703 older adults with coexisting mild cognitive impairment and moderate to severe hearing loss, hearing aids did not significantly reduce dementia incidence over 24 months. Participants in Shanghai, China, who had a mean age of 74.53 years, were assigned to either a hearing aid intervention (n = 353) or hearing care education (n = 350). Conversion to dementia-level impairment occurred in 3.09% of the hearing aid group compared with 4.74% of the control group (P = .23). In prespecified secondary analyses, the rate of cognitive improvement was 15.34% in the hearing aid group compared with 2.36% in the education group. A total of 610 participants completed the trial, and no study-related adverse events were reported.

Why it matters

Hearing loss is a prominent modifiable risk factor for cognitive decline in late life. These results provide controlled evidence on whether sensory interventions can slow or alter cognitive decline in older adults who already present with mild cognitive impairment.

Caveats

The trial used an open-label design and evaluated conversion over 24 months, which yielded low overall event numbers. The study was conducted at clinical and community sites in a single city, which may limit generalizability.

The paper

Hearing Intervention for Older Adults With Mild Cognitive Impairment: The CHOICE Randomized Clinical Trial