Wen Lu

Shanghai Jiao Tong University2 papersORCID 0000-0001-6964-1947OpenAlex

Papers

JAMA NeurologyHuman trial

Hearing aids did not cut dementia conversion in older adults

Over 24 months, dementia conversion was 3.09% with hearing aids compared with 4.74% with hearing care education, a non-significant difference.Over 24 months, dementia conversion was 3.09% with hearing aids compared with 4.74% with hearing care education, a non-significant difference.

CNS Neuroscience & TherapeuticsAnimals

Chronic stress accelerates Alzheimer pathology in mice by hyperactivating mTORC1

Inhibiting mTORC1 restored autophagy, reduced amyloid accumulation, and corrected circuit desynchronization and behavioral deficits in stressed…Inhibiting mTORC1 restored autophagy, reduced amyloid accumulation, and corrected circuit desynchronization and behavioral deficits in stressed Alzheimer model mice.