Walnut oligopeptides

1. Walnut oligopeptides increase mitochondrial DNA in mice.

   “increase the mitochondrial DNA content, as well as the expression levels of AMPK, PGC-1α, NRF-1 and TFAM in the gastrocnemius muscle of aging mice”

   AnimalsSAMP8 micesolutiongastrocnemius muscle110, 220 or 440 mg/kg·bwsix months

   Beneficial Effects of Walnut Oligopeptides on Muscle Loss in Senescence-Accelerated Mouse Prone-8 (SAMP8) Mice: Focusing on Mitochondrial Function

   Nutrients·13 May 2022

More on Mitochondrial DNA

1. Walnut oligopeptides decrease IL-1β in mice.

   “WOPs could significantly reduce the levels of IL-1β, IL-6 and TNF-α in serum and gastrocnemius tissues”

   AnimalsSAMP8 micesolutionserum and gastrocnemius muscle110, 220 or 440 mg/kg·bwsix months

   Beneficial Effects of Walnut Oligopeptides on Muscle Loss in Senescence-Accelerated Mouse Prone-8 (SAMP8) Mice: Focusing on Mitochondrial Function

   Nutrients·13 May 2022

More on IL-1β

1. Walnut oligopeptides improve physical function in mice.

   “WOPs could significantly increase muscle mass and improve physical performance (wire hang and catwalk behavioral tests) in aging mice.”

   AnimalsSAMP8 micesolution110, 220 or 440 mg/kg·bwsix months

   Beneficial Effects of Walnut Oligopeptides on Muscle Loss in Senescence-Accelerated Mouse Prone-8 (SAMP8) Mice: Focusing on Mitochondrial Function

   Nutrients·13 May 2022

1. Walnut oligopeptides increase muscle mass in mice.

   “WOPs could significantly increase muscle mass and improve physical performance (wire hang and catwalk behavioral tests) in aging mice.”

   AnimalsSAMP8 micesolution110, 220 or 440 mg/kg·bwsix months

   Beneficial Effects of Walnut Oligopeptides on Muscle Loss in Senescence-Accelerated Mouse Prone-8 (SAMP8) Mice: Focusing on Mitochondrial Function

   Nutrients·13 May 2022