Transcription
downin mouse cells1
Tyrosine inhibits transcription in mouse cells.
“While tyrosine facilitated topoisomerase 1 (TOP1) recruitment to chromatin and inhibited global transcription”
Cellsin neurons
IUBMB life1 Jun 2025
DNA repair
upin mouse cells1
Tyrosine activates DNA repair in mouse cells.
“Tyrosine and phenylalanine treatment decreased tubulin tyrosination, activated DNA repair pathways, and protected against etoposide (ETO) and camptothecin (CPT)-induced toxicity, respectively, in neurons.”
Cellsneurons
IUBMB life1 Jun 2025
Japan Society for the Promotion of ScienceJP¥9mFundacao de Amparo a Pesquisa do Estado de Sao Paulo
Functional analysis of the receptor tyrosine kinase Kit in epidermis and hair cycle
Japan Society for the Promotion of ScienceGifu UniversityJP¥4.7m2023–2026
Fundacao de Amparo a Pesquisa do Estado de Sao PauloHospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo2021–2024
Evaluation of the impact of autophagy-mediated tyrosine kinase Fyn on sarcopenia.
Japan Society for the Promotion of ScienceGunma UniversityJP¥4.3m2020–2023
People starting nilotinib, a leukaemia drug, had a hazard ratio of 0.37 for neurodegenerative disease diagnosis or death versus matched people without chronic myeloid…People starting nilotinib, a leukaemia drug, had a hazard ratio of 0.37 for neurodegenerative disease diagnosis or death versus matched people without chronic myeloid leukaemia.
A drug screen in human connective-tissue cells linked the selective killing effect to a protein that receives growth signals.A drug screen in human connective-tissue cells linked the selective killing effect to a protein that receives growth signals.