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TM5441

Intervention

1 paper

PubChem 44250349

  • Animals1

Mouse lifespan

NIA ITP
  • 201460 ppm from 11 months−4% males, 0% females

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 1Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 01 in 12 months
Cell Death Discovery·12 Mar

Targeting oncogene-induced senescence in ETV6::RUNX1 pre-leukemic cells

Experiments in miceLeukemia
Paper

Related

  • Apoptosis1
  • CASP31
  • Cell cycle regulation1
  • Cellular senescence1
  • DNA damage response1
  • ETV61
  • ETV6::RUNX11
  • H2AX1
  • Oxidative stress and ROS signalling1
  • RUNX11
  • SASP1
  • SERPINE11
  • Senescence-associated secretory phenotype (SASP)1
  • TP531
  • gamma-H2AX1
  • Leukemia1
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