ETV6::RUNX1
1 paper1 finding
- 1 lab in 2 countries
- Funders: Agencia Estatal de Investigación and 7 more
- Animals1
Effects
1Cellular senescence
upin mouse cells1
1 study
Cellular senescence
upin mouse cells1
ETV6::RUNX1 induces cellular senescence in mouse cells.
“We observed that E::R caused a senescence-like phenotype in BaF3 cells, characterized by altered morphology, increased β-galactosidase activity, elevated reactive oxygen species (ROS) and Senescence-Associated Secretory Phenotype (SASP) factor secretion.”
Cellsin BaF3 and immature hematopoietic cells
Targeting oncogene-induced senescence in ETV6::RUNX1 pre-leukemic cells
Cell death discovery11 Mar 2026
Latest
1 in 12 monthsCell Death Discovery
Targeting oncogene-induced senescence in ETV6::RUNX1 pre-leukemic cells
Experiments in miceLeukemia