ETV6::RUNX1

Gene

1 paper1 finding

  • 1 lab in 2 countries
  • Funders: Agencia Estatal de Investigación and 7 more
  • Animals1

Effects

1

Cellular senescence

upin mouse cells1

1 study
  1. ETV6::RUNX1 induces cellular senescence in mouse cells.

    “We observed that E::R caused a senescence-like phenotype in BaF3 cells, characterized by altered morphology, increased β-galactosidase activity, elevated reactive oxygen species (ROS) and Senescence-Associated Secretory Phenotype (SASP) factor secretion.”

    Cellsin BaF3 and immature hematopoietic cells

    Targeting oncogene-induced senescence in ETV6::RUNX1 pre-leukemic cells

    Cell death discovery11 Mar 2026

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