SRN-901

Intervention

1 paper3 findings

  • 1 lab in 1 country
  • 3 of 3 findings with company ties
  • Animals1

Outcomes

2

Frailty

downin mice1

1 study
  1. SRN-901 protects against frailty in mice (70% attenuation, p < 0.001).

    “SRN-901 protected mice against increased frailty during aging, with baseline-normalized scores rising to 1.17 in treated mice and 1.57 in controls, corresponding to a 70% attenuation of frailty progression”

    Animalsfed a Western dietbetween pre-treatment (D-14) and post-treatment (D128)

    SRN-901, a Novel Longevity Drug, Extends Lifespan and Healthspan by Targeting Multiple Aging Pathways

    Drug design, development and therapy15 Apr 2026

Median remaining lifespan

upin mice1+33% median remaining lifespan

1 study
  1. SRN-901 extends median remaining lifespan in mice (+33% median remaining lifespan).

    “SRN-901-treated mice showed a significant increase of 33% in median remaining lifespan compared to placebo-treated mice.”

    Animalsfed a Western diet

    SRN-901, a Novel Longevity Drug, Extends Lifespan and Healthspan by Targeting Multiple Aging Pathways

    Drug design, development and therapy15 Apr 2026

Associations

1

Mortality

downin mice1HR 0.54

1 study
  1. SRN-901 lowers the risk of mortality in mice (HR 0.54, 46% reduction).

    “Cox proportional hazards analysis revealed a hazard ratio of 0.54, indicating that SRN-901 treatment was associated with a 46% reduction in the hazard of death.”

    Animalsfed a Western diet

    SRN-901, a Novel Longevity Drug, Extends Lifespan and Healthspan by Targeting Multiple Aging Pathways

    Drug design, development and therapy15 Apr 2026

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