SRN-901
1 paper3 findings
- 1 lab in 1 country
- 3 of 3 findings with company ties
- Animals1
Outcomes
2Frailty
downin mice1
1 study
Frailty
downin mice1
SRN-901 protects against frailty in mice (70% attenuation, p < 0.001).
“SRN-901 protected mice against increased frailty during aging, with baseline-normalized scores rising to 1.17 in treated mice and 1.57 in controls, corresponding to a 70% attenuation of frailty progression”
Animalsfed a Western dietbetween pre-treatment (D-14) and post-treatment (D128)
Drug design, development and therapy15 Apr 2026
Median remaining lifespan
upin mice1+33% median remaining lifespan
1 study
Median remaining lifespan
upin mice1+33% median remaining lifespan
SRN-901 extends median remaining lifespan in mice (+33% median remaining lifespan).
“SRN-901-treated mice showed a significant increase of 33% in median remaining lifespan compared to placebo-treated mice.”
Animalsfed a Western diet
Drug design, development and therapy15 Apr 2026
Associations
1Mortality
downin mice1HR 0.54
1 study
Mortality
downin mice1HR 0.54
SRN-901 lowers the risk of mortality in mice (HR 0.54, 46% reduction).
“Cox proportional hazards analysis revealed a hazard ratio of 0.54, indicating that SRN-901 treatment was associated with a 46% reduction in the hazard of death.”
Animalsfed a Western diet
Drug design, development and therapy15 Apr 2026
Latest
1 in 12 monthsDrug Design, Development and Therapy
SRN-901, a Novel Longevity Drug, Extends Lifespan and Healthspan by Targeting Multiple Aging Pathways
Experiments in miceInterventions