Soluble DLK1

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Animals1

Outcomes

1

Oligodendrocyte maturation

downin human cells1

1 study
  1. Soluble DLK1 impairs oligodendrocyte maturation in human cells.

    “In human iPSC systems, sDLK1 impaired oligodendrocyte maturation and altered calcium signaling in excitatory neurons.”

    Cellshuman iPSC systemsoligodendrocyte

    Soluble DLK1 secreted by telomere-shortening-induced senescent microglia impairs oligodendrocyte functions and alters neuronal activity

    bioRxiv (Cold Spring Harbor Laboratory)15 Jan 2026Preprint

Associations

1

calcium signaling pathway

mixedin human cells1

1 study
  1. Soluble DLK1 is associated with calcium signaling pathway in human cells.

    “In human iPSC systems, sDLK1 impaired oligodendrocyte maturation and altered calcium signaling in excitatory neurons.”

    Cellshuman iPSC systemsexcitatory neuron

    Soluble DLK1 secreted by telomere-shortening-induced senescent microglia impairs oligodendrocyte functions and alters neuronal activity

    bioRxiv (Cold Spring Harbor Laboratory)15 Jan 2026Preprint

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