Calcium signaling
Biomarker1 paper1 finding
- Model organisms1
Upstream
1TyrR
upin flies1
1 study
TyrR
upin flies1
TyrR activates calcium signaling in flies.
“Selective Tyr1R overexpression in (nor)adrenergic-like Tdc2 neurons prolonged lifespan, restored Ca2+ signalling and improved locomotor performance.”
Model organismsselective Tyr1R overexpression in Tdc2 neuronsTdc2 neurons
Restoring Tyr1R signaling aids motor function in flies · bioRxiv · 5 Oct 2026 · Preprint
Latest
3Restoring Tyr1R signaling aids motor function in flies
Overexpressing the receptor in adrenergic-like neurons prolonged lifespan, restored calcium signaling, and improved locomotor performance in aged…Overexpressing the receptor in adrenergic-like neurons prolonged lifespan, restored calcium signaling, and improved locomotor performance in aged fruit flies.
Calcium overload impairs muscle regeneration by driving sustained NFAT signaling
Inhibiting NFAT restored myoblast differentiation in culture and improved myofiber repair in injured mice.Inhibiting NFAT restored myoblast differentiation in culture and improved myofiber repair in injured mice.
Chelating intracellular calcium reduces fibroblast senescence and eases lung fibrosis
Treating cells and an in vivo fibrosis model with a calcium chelator delayed senescence markers, reduced collagen buildup, and dampened inflammatory…Treating cells and an in vivo fibrosis model with a calcium chelator delayed senescence markers, reduced collagen buildup, and dampened inflammatory secretions.