Senescent renal tubular epithelial cell conditioned medium

Intervention1 paper1 finding

  • Cells1

Outcomes

1

Renal fibroblast activation and extracellular matrix gene expression

upin cells1Very low certainty

1 study
  1. Senescent renal tubular epithelial cell conditioned medium increases renal fibroblast activation and extracellular matrix gene expression in cells.

    Cellsmedium from 1-aminopyrene-induced senescent renal tubular epithelial cellsconditioned mediumrenal fibroblast

    Diesel-derived chemical triggers scarring signals in kidney cells · Journal of biochemical and molecular toxicology · 1 Oct 2026

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Journal of Biochemical and Molecular ToxicologyCells

Diesel-derived chemical triggers scarring signals in kidney cells

Experiments in kidney cells grown in the lab found that a diesel exhaust breakdown product caused lasting DNA damage and signals that activated…Experiments in kidney cells grown in the lab found that a diesel exhaust breakdown product caused lasting DNA damage and signals that activated connective-tissue cells.